7q: HIV-2 is more closely related phylogenetically to which virus ?
a. HIV-1 of chimpanzees
b. Simian immunodeficiency virus ( SIV ) in sooty mangabeys
c. SIV in sykes
d. SIV in African green monkeys
8q: what are the two major envelope proteins that surround the HIV virion ?
a. gp 120 and gp 40
b. gp 120 and gp 41
c. gp 120 and gp 42
d. gp 120 and gp 43
9q: all of the following are true about HIV except ?
a. it is a DNA virus
b. it has the enzyme reverse transcriptase
c. the gp120 protein binds to the host cell via the receptor called CD4 molecule
d. the CD4 molecule is a protein found predominantly on a subset of T lymphocytes
e. the CD4 is also present on monocytes/macrophages and dendritic/langerhans cells
10q: once gp120 binds to CD4 , the gp120 undergoes a conformational change that facilitates binding to one of a group of co-receptors . what are the two major co-receptors to which HIV attaches ?
a. CCR5 and CXCR4
b. CCR6 and CXCR5
c. CCR7 and CXCR6
d. CCR8 and CXCR7
